منابع مشابه
A Road Map
Researchers in the organizational sciences and in the social and behavioral sciences in general encounter a host of problems as they seek to describe, predict, and understand behavior. The procedures we use to measure and analyze behavior are constantly improving as a result of the efforts of psychometricians and applied statisticians, among others. Many of the techniques discussed in this book...
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S enthil Muthuswamy has traveled far from the small town in southern India where he grew up: all the way to ground zero in the fi ght against cancer. His work is laying a path toward a new understanding of the role of cell polarity in tumorigenesis (1, 2). Senthil's journey to his new stomp-ing grounds started at an agricultural school in India. It took him through his PhD with William Muller a...
متن کاملA Road Map for Precision Cancer Medicine Using Personalized Models.
A study by Pauli and colleagues in this issue of Cancer Discovery describes the creation of a precision cancer platform for patients with advanced disease, integrating DNA sequencing of patient tumors with the generation of patient-derived organoids and xenografts. They propose the use of this platform for drug testing to nominate therapeutic options for individual patients and for therape...
متن کاملA self-updating road map of The Cancer Genome Atlas
MOTIVATION Since 2011, The Cancer Genome Atlas' (TCGA) files have been accessible through HTTP from a public site, creating entirely new possibilities for cancer informatics by enhancing data discovery and retrieval. Significantly, these enhancements enable the reporting of analysis results that can be fully traced to and reproduced using their source data. However, to realize this possibility,...
متن کاملCancer Theranostics: An Introduction
Theranostics is a portmanteau of therapeutics and diagnostics. It can be diagnosis followed by therapy to stratify patients who will likely respond to a given treatment. It can also be therapy followed by diagnosis to monitor early response to treatment and predict treatment efficacy. It is also possible that diagnostics and therapeutics are codeveloped. For example, nanoplatforms can be design...
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ژورنال
عنوان ژورنال: Public Health Genomics
سال: 2017
ISSN: 1662-4246,1662-8063
DOI: 10.1159/000478253